Chidamide-Induced Accumulation of Reactive Oxygen Species Increases Lenalidomide Sensitivity Against Multiple Myeloma Cells

BACKGROUND: Lenalidomide, an immunomodulatory drug (IMiD), is an effective therapy for the treatment of multiple myeloma (MM). However, prolonged treatment may be accompanied by toxicity, second primary malignancies, and drug resistance. There is an inherent vulnerability in MM cells that high rates...

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Detalles Bibliográficos
Autores principales: Jiang, Duanfeng, Zhang, Kaixuan, Zhu, Yinghong, Zhu, Yan, Zou, Lang, Hu, Jian, Cui, Yajuan, Zhou, Wen, Chen, Fangping, He, Yanjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274322/
https://www.ncbi.nlm.nih.gov/pubmed/34262292
http://dx.doi.org/10.2147/OTT.S312249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274322/
https://www.ncbi.nlm.nih.gov/pubmed/34262292
http://dx.doi.org/10.2147/OTT.S312249

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