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Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA

BACKGROUND: Early cancer detection could identify tumors at a time when outcomes are superior and treatment is less morbid. This prospective case-control sub-study (from NCT02889978 and NCT03085888) assessed the performance of targeted methylation analysis of circulating cell-free DNA (cfDNA) to det...

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Detalles Bibliográficos
Autores principales: Liu, M. C., Oxnard, G. R., Klein, E. A., Swanton, C., Seiden, M. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274402/
https://www.ncbi.nlm.nih.gov/pubmed/33506766
http://dx.doi.org/10.1016/j.annonc.2020.02.011