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Congenital Asplenia Interrupts Immune Homeostasis and Leads to Excessive Systemic Inflammation in Zebrafish

Splenectomy or congenital asplenia in humans increases susceptibility to infections. We have previously reported that congenital asplenia in zebrafish reduces resistance to Aeromonas hydrophila infection. However, the molecular mechanism of systemic immune response in congenitally asplenic individua...

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Detalles Bibliográficos
Autores principales: Xie, Lang, Chen, Zheyu, Guo, Hui, Tao, Yixi, Miao, Xiaomin, Wu, Ronghua, Li, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274418/
https://www.ncbi.nlm.nih.gov/pubmed/34262881
http://dx.doi.org/10.3389/fcimb.2021.668859