Sustained localized delivery of immunotherapy to lymph nodes reverses immunosuppression and increases long-term survival in murine glioblastoma

INTRODUCTION: Despite the advent of immunotherapy as a promising therapeutic, glioblastoma (GBM) remains resistant to using checkpoint blockade due to its highly immunosuppressive tumor milieu. Moreover, current anti-PD-1 treatment requires multiple infusions with adverse systemic effects. Therefore...

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Detalles Bibliográficos
Autores principales: Choi, John, Pant, Ayush, Medikonda, Ravi, Kim, Young-Hoon, Routkevitch, Denis, Saleh, Laura, Tong, Luqing, Chan, Hok Yee, Nedrow, Jessie, Jackson, Christopher, Jackson, Christina, Lim, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274437/
https://www.ncbi.nlm.nih.gov/pubmed/34290904
http://dx.doi.org/10.1080/2162402X.2021.1940673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274437/
https://www.ncbi.nlm.nih.gov/pubmed/34290904
http://dx.doi.org/10.1080/2162402X.2021.1940673

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