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Pyridoxal kinase and poly(ADP-ribose) affect the immune microenvironment of locally advanced cancers

Malignant cells adapt to the hostile tumor microenvironment by escaping from, or actively suppressing, anticancer immune responses. In the past, we reported that reduced synthesis of active vitamin B6 (due to downregulation of pyridoxal kinase) or overactivation of poly(ADP-ribose) polymerase confer...

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Detalles Bibliográficos
Autores principales: Joseph, Adrien, Pan, Juncheng, Michels, Judith, Kroemer, Guido, Castedo, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274443/
https://www.ncbi.nlm.nih.gov/pubmed/34290910
http://dx.doi.org/10.1080/2162402X.2021.1950954