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Identification of imidazo[4,5-c]pyridin-2-one derivatives as novel Src family kinase inhibitors against glioblastoma

Glioblastoma multiforme (GBM) is the most common and malignant primary brain tumour in the central nervous system (CNS). As the ideal targets for GBM treatment, Src family kinases (SFKs) have attracted much attention. Herein, a new series of imidazo[4,5-c]pyridin-2-one derivatives were designed and...

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Detalles Bibliográficos
Autores principales: Zhang, Lishun, Yang, Zichao, Sang, Huiting, Jiang, Ying, Zhou, Mingfeng, Huang, Chuan, Huang, Chunhui, Wu, Xiaoyun, Zhang, Tingting, Zhang, Xingmei, Wan, Shanhe, Zhang, Jiajie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274516/
https://www.ncbi.nlm.nih.gov/pubmed/34238111
http://dx.doi.org/10.1080/14756366.2021.1948542