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Potent RBD-specific neutralizing rabbit monoclonal antibodies recognize emerging SARS-CoV-2 variants elicited by DNA prime-protein boost vaccination

Global concerns arose as the emerged and rapidly spreading SARS-CoV-2 variants might escape host immunity induced by vaccination. In this study, a heterologous prime-boost immunization strategy for COVID-19 was designed to prime with a DNA vaccine encoding wild type (WT) spike protein receptor-bindi...

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Detalles Bibliográficos
Autores principales: Chen, Yuxin, Zhu, Liguo, Huang, Weijin, Tong, Xin, Wu, Hai, Tao, Yue, Tong, Bei, Huang, Haibin, Chen, Jiachen, Zhao, Xiangan, Lou, Yang, Wu, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274519/
https://www.ncbi.nlm.nih.gov/pubmed/34120577
http://dx.doi.org/10.1080/22221751.2021.1942227