New horizons in drug discovery of lymphocyte-specific protein tyrosine kinase (Lck) inhibitors: a decade review (2011–2021) focussing on structure–activity relationship (SAR) and docking insights

Lymphocyte-specific protein tyrosine kinase (Lck), a non-receptor Src family kinase, has a vital role in various cellular processes such as cell cycle control, cell adhesion, motility, proliferation, and differentiation. Lck is reported as a key factor regulating the functions of T-cell including th...

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Detalles Bibliográficos
Autores principales: Elkamhawy, Ahmed, Ali, Eslam M. H., Lee, Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274522/
https://www.ncbi.nlm.nih.gov/pubmed/34233563
http://dx.doi.org/10.1080/14756366.2021.1937143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274522/
https://www.ncbi.nlm.nih.gov/pubmed/34233563
http://dx.doi.org/10.1080/14756366.2021.1937143

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