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Esculin protects against methionine choline-deficient diet-induced non-alcoholic steatohepatitis by regulating the Sirt1/NF-[Image: see text] B p65 pathway

CONTEXT: Esculin, an active coumarin compound, has been demonstrated to exert anti-inflammatory effects. However, its potential role in non-alcoholic steatohepatitis (NASH) remains unclear. OBJECTIVE: This study explored the hepatoprotective effect and the molecular mechanism of esculin in methionin...

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Detalles Bibliográficos
Autores principales: Yang, Xi-Ding, Chen, Zhuo, Ye, Ling, Chen, Jing, Yang, Yong-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274538/
https://www.ncbi.nlm.nih.gov/pubmed/34243681
http://dx.doi.org/10.1080/13880209.2021.1945112