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Targeting cancer associated fibroblasts to enhance immunotherapy: emerging strategies and future perspectives

Cancer associated fibroblasts are a prominent component of the tumour microenvironment in most solid cancers. This heterogeneous population of cells are known to play an important role in tumour progression and recent studies have demonstrated that CAFs may confer resistance to checkpoint immunother...

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Detalles Bibliográficos
Autores principales: Hanley, Christopher J., Thomas, Gareth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274722/
https://www.ncbi.nlm.nih.gov/pubmed/34262652
http://dx.doi.org/10.18632/oncotarget.27936