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A novel high-throughput screen for identifying lipids that stabilise membrane proteins in detergent based solution
Membrane proteins have a range of crucial biological functions and are the target of about 60% of all prescribed drugs. For most studies, they need to be extracted out of the lipid-bilayer, e.g. by detergent solubilisation, leading to the loss of native lipids, which may disturb important protein-li...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274869/ https://www.ncbi.nlm.nih.gov/pubmed/34252116 http://dx.doi.org/10.1371/journal.pone.0254118 |