Metformin Inhibits Lipoteichoic Acid–Induced Oxidative Stress and Inflammation Through AMPK/NRF2/NF-κB Signaling Pathway in Bovine Mammary Epithelial Cells

The objective of this research was to explore the effect of metformin on the lipoteichoic acid (LTA)–induced mastitis model using isolated primary bovine mammary epithelial cells (PBMECs). The PBMECs were exposed to either 3 mM metformin for 12 h as a metformin group (MET) or 100 μg/mL LTA for 6 h a...

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Detalles Bibliográficos
Autores principales: Arbab, Abdelaziz Adam Idriss, Lu, Xubin, Abdalla, Ismail Mohamed, Idris, Amer Adam, Chen, Zhi, Li, Mingxun, Mao, Yongjiang, Xu, Tianle, Yang, Zhangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Veterinary Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274905/
https://www.ncbi.nlm.nih.gov/pubmed/34262962
http://dx.doi.org/10.3389/fvets.2021.661380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274905/
https://www.ncbi.nlm.nih.gov/pubmed/34262962
http://dx.doi.org/10.3389/fvets.2021.661380

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