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Metformin Inhibits Lipoteichoic Acid–Induced Oxidative Stress and Inflammation Through AMPK/NRF2/NF-κB Signaling Pathway in Bovine Mammary Epithelial Cells
The objective of this research was to explore the effect of metformin on the lipoteichoic acid (LTA)–induced mastitis model using isolated primary bovine mammary epithelial cells (PBMECs). The PBMECs were exposed to either 3 mM metformin for 12 h as a metformin group (MET) or 100 μg/mL LTA for 6 h a...
Autores principales: | Arbab, Abdelaziz Adam Idriss, Lu, Xubin, Abdalla, Ismail Mohamed, Idris, Amer Adam, Chen, Zhi, Li, Mingxun, Mao, Yongjiang, Xu, Tianle, Yang, Zhangping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274905/ https://www.ncbi.nlm.nih.gov/pubmed/34262962 http://dx.doi.org/10.3389/fvets.2021.661380 |
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