A Novel Biological Activity of the STAT3 Inhibitor Stattic in Inhibiting Glutathione Reductase and Suppressing the Tumorigenicity of Human Cervical Cancer Cells via a ROS-Dependent Pathway

INTRODUCTION: Glutathione reductase (GSR) provides reduced glutathione (GSH) to maintain redox homeostasis. Inhibition of GSR disrupts this balance, resulting in cell damage, which benefits cancer therapy. However, the effect of GSR inhibition on the tumorigenicity of human cervical cancer is not fu...

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Detalles Bibliográficos
Autores principales: Xia, Yuchen, Wang, Guihua, Jiang, Manli, Liu, Xueting, Zhao, Yan, Song, Yinghui, Jiang, Binyuan, Zhu, Demao, Hu, Ling, Zhang, Zhao, Cao, Ting, Wang, Ji Ming, Hu, Jinyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275107/
https://www.ncbi.nlm.nih.gov/pubmed/34262291
http://dx.doi.org/10.2147/OTT.S313507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275107/
https://www.ncbi.nlm.nih.gov/pubmed/34262291
http://dx.doi.org/10.2147/OTT.S313507

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