Development and Validation of a Simple and Sensitive LC-MS/MS Method for Quantification of Metformin in Dried Blood Spot Its Application as an Indicator for Medication Adherence

OBJECTIVE: Metformin (MET), an oral biguanide agent, can improve insulin resistance and decrease hepatic glucose production, leading to a reduction in blood-sugar levels. The objective of the present study was to develop and validate simple and rapid LC-MS/MS method for analysis of MET in dried bloo...

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Detalles Bibliográficos
Autores principales: ALquadeib, Bushra T, Aloudah, Nouf M, Almurshedi, Alanood S, ALfagih, Iman M, ALdosari, Basmah N, ALmeleky, Adim S, Almubyedh, Nour M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275188/
https://www.ncbi.nlm.nih.gov/pubmed/34267540
http://dx.doi.org/10.2147/IJGM.S312633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275188/
https://www.ncbi.nlm.nih.gov/pubmed/34267540
http://dx.doi.org/10.2147/IJGM.S312633

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