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Myocarditis Induced by Immune Checkpoint Inhibitors: Mechanisms and Therapeutic Prospects

Under physiological conditions, immune checkpoint molecules downregulate the activation and effector function of myocardial antigen-reactive T cells through an immunosuppressive pathway, thus enabling myocardial T cells to maintain immune homeostasis under the action of central and peripheral tolera...

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Detalles Bibliográficos
Autores principales: Zou, Wenlu, Lu, Jie, Hao, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275200/
https://www.ncbi.nlm.nih.gov/pubmed/34267536
http://dx.doi.org/10.2147/JIR.S311616