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Myocarditis Induced by Immune Checkpoint Inhibitors: Mechanisms and Therapeutic Prospects
Under physiological conditions, immune checkpoint molecules downregulate the activation and effector function of myocardial antigen-reactive T cells through an immunosuppressive pathway, thus enabling myocardial T cells to maintain immune homeostasis under the action of central and peripheral tolera...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275200/ https://www.ncbi.nlm.nih.gov/pubmed/34267536 http://dx.doi.org/10.2147/JIR.S311616 |