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Resolving diverse protein–DNA footprints from exonuclease-based ChIP experiments

MOTIVATION: High-throughput chromatin immunoprecipitation (ChIP) sequencing-based assays capture genomic regions associated with the profiled transcription factor (TF). ChIP-exo is a modified protocol, which uses lambda exonuclease to digest DNA close to the TF-DNA complex, in order to improve on th...

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Detalles Bibliográficos
Autores principales: Biswas, Anushua, Narlikar, Leelavati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275329/
https://www.ncbi.nlm.nih.gov/pubmed/34252930
http://dx.doi.org/10.1093/bioinformatics/btab274