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A novel constrained genetic algorithm-based Boolean network inference method from steady-state gene expression data
MOTIVATION: It is a challenging problem in systems biology to infer both the network structure and dynamics of a gene regulatory network from steady-state gene expression data. Some methods based on Boolean or differential equation models have been proposed but they were not efficient in inference o...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275338/ https://www.ncbi.nlm.nih.gov/pubmed/34252959 http://dx.doi.org/10.1093/bioinformatics/btab295 |