scPNMF: sparse gene encoding of single cells to facilitate gene selection for targeted gene profiling

MOTIVATION: Single-cell RNA sequencing (scRNA-seq) captures whole transcriptome information of individual cells. While scRNA-seq measures thousands of genes, researchers are often interested in only dozens to hundreds of genes for a closer study. Then, a question is how to select those informative g...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Dongyuan, Li, Kexin, Hemminger, Zachary, Wollman, Roy, Li, Jingyi Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Regulatory and Functional Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275345/
https://www.ncbi.nlm.nih.gov/pubmed/34252925
http://dx.doi.org/10.1093/bioinformatics/btab273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275345/
https://www.ncbi.nlm.nih.gov/pubmed/34252925
http://dx.doi.org/10.1093/bioinformatics/btab273

Ejemplares similares