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scPNMF: sparse gene encoding of single cells to facilitate gene selection for targeted gene profiling
MOTIVATION: Single-cell RNA sequencing (scRNA-seq) captures whole transcriptome information of individual cells. While scRNA-seq measures thousands of genes, researchers are often interested in only dozens to hundreds of genes for a closer study. Then, a question is how to select those informative g...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275345/ https://www.ncbi.nlm.nih.gov/pubmed/34252925 http://dx.doi.org/10.1093/bioinformatics/btab273 |