Long reads capture simultaneous enhancer–promoter methylation status for cell-type deconvolution

MOTIVATION: While promoter methylation is associated with reinforcing fundamental tissue identities, the methylation status of distant enhancers was shown by genome-wide association studies to be a powerful determinant of cell-state and cancer. With recent availability of long reads that report on t...

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Detalles Bibliográficos
Autores principales: Margalit, Sapir, Abramson, Yotam, Sharim, Hila, Manber, Zohar, Bhattacharya, Surajit, Chen, Yi-Wen, Vilain, Eric, Barseghyan, Hayk, Elkon, Ran, Sharan, Roded, Ebenstein, Yuval
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Regulatory and Functional Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275347/
https://www.ncbi.nlm.nih.gov/pubmed/34252972
http://dx.doi.org/10.1093/bioinformatics/btab306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275347/
https://www.ncbi.nlm.nih.gov/pubmed/34252972
http://dx.doi.org/10.1093/bioinformatics/btab306

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