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Thermodynamic modeling reveals widespread multivalent binding by RNA-binding proteins
MOTIVATION: Understanding how proteins recognize their RNA targets is essential to elucidate regulatory processes in the cell. Many RNA-binding proteins (RBPs) form complexes or have multiple domains that allow them to bind to RNA in a multivalent, cooperative manner. They can thereby achieve higher...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275352/ https://www.ncbi.nlm.nih.gov/pubmed/34252974 http://dx.doi.org/10.1093/bioinformatics/btab300 |