Development, Characterization, and Evaluation of SLN-Loaded Thermoresponsive Hydrogel System of Topotecan as Biological Macromolecule for Colorectal Delivery

BACKGROUND: Chemotherapeutic drugs cause severe toxicities if administered unprotected, without proper targeting, and controlled release. In this study, we developed topotecan- (TPT-) loaded solid lipid nanoparticles (SLNs) for their chemotherapeutic effect against colorectal cancer. The TPT-SLNs we...

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Detalles Bibliográficos
Autores principales: Xing, R., Mustapha, O., Ali, T., Rehman, M., Zaidi, S. S., Baseer, A., Batool, S., Mukhtiar, M., Shafique, S., Malik, M., Sohail, S., Ali, Z., Zahid, F., Zeb, A., Shah, F., Yousaf, A., Din, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275402/
https://www.ncbi.nlm.nih.gov/pubmed/34285920
http://dx.doi.org/10.1155/2021/9968602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275402/
https://www.ncbi.nlm.nih.gov/pubmed/34285920
http://dx.doi.org/10.1155/2021/9968602

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