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The Transcription Factor PfAP2-O Influences Virulence Gene Transcription and Sexual Development in Plasmodium falciparum

The human malaria parasite Plasmodium falciparum expresses variant PfEMP1 proteins on the infected erythrocyte, which function as ligands for endothelial receptors in capillary vessels, leading to erythrocyte sequestration and severe malaria. The factors that orchestrate the mono-allelic expression...

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Detalles Bibliográficos
Autores principales: Cubillos, Eliana F. G., Prata, Isadora Oliveira, Fotoran, Wesley Luzetti, Ranford-Cartwright, Lisa, Wunderlich, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275450/
https://www.ncbi.nlm.nih.gov/pubmed/34268135
http://dx.doi.org/10.3389/fcimb.2021.669088