In silico comparison of pharmacokinetic properties of three extended half-life factor IX concentrates

PURPOSE: Pharmacokinetic (PK) differences between the extended half-life (EHL) factor IX (FIX) concentrates for hemophilia B exist, which may influence hemostatic efficacy of replacement therapy in patients. Therefore, we aimed to evaluate the PK properties of three EHL-FIX concentrates and compare...

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Detalles Bibliográficos
Autores principales: Preijers, Tim, Bukkems, Laura, van Spengler, Max, Leebeek, Frank, Cnossen, Marjon, Mathôt, Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Pharmacokinetics and Disposition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275546/
https://www.ncbi.nlm.nih.gov/pubmed/33624121
http://dx.doi.org/10.1007/s00228-021-03111-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275546/
https://www.ncbi.nlm.nih.gov/pubmed/33624121
http://dx.doi.org/10.1007/s00228-021-03111-2

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