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In silico comparison of pharmacokinetic properties of three extended half-life factor IX concentrates

PURPOSE: Pharmacokinetic (PK) differences between the extended half-life (EHL) factor IX (FIX) concentrates for hemophilia B exist, which may influence hemostatic efficacy of replacement therapy in patients. Therefore, we aimed to evaluate the PK properties of three EHL-FIX concentrates and compare...

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Detalles Bibliográficos
Autores principales:	Preijers, Tim, Bukkems, Laura, van Spengler, Max, Leebeek, Frank, Cnossen, Marjon, Mathôt, Ron
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Pharmacokinetics and Disposition
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275546/ https://www.ncbi.nlm.nih.gov/pubmed/33624121 http://dx.doi.org/10.1007/s00228-021-03111-2

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