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Mitofusion is required for MOTS‐c induced GLUT4 translocation

MOTS‐c (mitochondrial ORF of the twelve S-c) is a 16-amino-acid mitochondrial peptide that has been shown to counter insulin resistance and alleviate obesity in vivo. However, the mechanisms involved in the pharmacological action of MOTS-c remain elusive. Based on the ability of MOTS-c to improve in...

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Detalles Bibliográficos
Autores principales: Bhullar, Khushwant S., Shang, Nan, Kerek, Evan, Wu, Kaiyu, Wu, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275580/
https://www.ncbi.nlm.nih.gov/pubmed/34253808
http://dx.doi.org/10.1038/s41598-021-93735-2