Morphological screening of mesenchymal mammary tumor organoids to identify drugs that reverse epithelial-mesenchymal transition

The epithelial-mesenchymal transition (EMT) has been implicated in conferring stem cell properties and therapeutic resistance to cancer cells. Therefore, identification of drugs that can reprogram EMT may provide new therapeutic strategies. Here, we report that cells derived from claudin-low mammary...

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Detalles Bibliográficos
Autores principales: Zhao, Na, Powell, Reid T., Yuan, Xueying, Bae, Goeun, Roarty, Kevin P., Stossi, Fabio, Strempfl, Martina, Toneff, Michael J., Johnson, Hannah L., Mani, Sendurai A., Jones, Philip, Stephan, Clifford C., Rosen, Jeffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275587/
https://www.ncbi.nlm.nih.gov/pubmed/34253738
http://dx.doi.org/10.1038/s41467-021-24545-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275587/
https://www.ncbi.nlm.nih.gov/pubmed/34253738
http://dx.doi.org/10.1038/s41467-021-24545-3

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