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CtBP1/2 differentially regulate genomic stability and DNA repair pathway in high-grade serous ovarian cancer cell

The C-terminal binding proteins (CtBPs), CtBP1 and CtBP2, are transcriptional co-repressor that interacts with multiple transcriptional factors to modulate the stability of chromatin. CtBP proteins were identified with overexpression in the high-grade serous ovarian carcinoma (HGSOC). However, littl...

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Detalles Bibliográficos
Autores principales: He, YingYing, He, Zhicheng, Lin, Jian, Chen, Cheng, Chen, Yuanzhi, Liu, Shubai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275597/
https://www.ncbi.nlm.nih.gov/pubmed/34253710
http://dx.doi.org/10.1038/s41389-021-00344-9