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Disruptor of telomeric silencing 1-like promotes ovarian cancer tumor growth by stimulating pro-tumorigenic metabolic pathways and blocking apoptosis

Ovarian cancer is the leading cause of gynecological malignancy-related deaths. Current therapies for ovarian cancer do not provide meaningful and sustainable clinical benefits, highlighting the need for new therapies. We show that the histone H3K79 methyltransferase disruptor of telomeric silencing...

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Detalles Bibliográficos
Autores principales: Chava, Suresh, Bugide, Suresh, Edwards, Yvonne J. K., Gupta, Romi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275629/
https://www.ncbi.nlm.nih.gov/pubmed/34253709
http://dx.doi.org/10.1038/s41389-021-00339-6