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Serotonin receptor 4 in the hippocampus modulates mood and anxiety

Serotonin receptor 4 (5-HT(4)R) plays an important role in regulating mood, anxiety, and cognition, and drugs that activate this receptor have fast-acting antidepressant (AD)-like effects in preclinical models. However, 5-HT(4)R is widely expressed throughout the central nervous system (CNS) and per...

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Detalles Bibliográficos
Autores principales: Karayol, Remzi, Medrihan, Lucian, Warner-Schmidt, Jennifer L., Fait, Ben W., Rao, Meghana N., Holzner, Eva B., Greengard, Paul, Heintz, Nathaniel, Schmidt, Eric F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275670/
https://www.ncbi.nlm.nih.gov/pubmed/33441982
http://dx.doi.org/10.1038/s41380-020-00994-y