Cargando…

TAZ inhibits osteoclastogenesis by attenuating TAK1/NF-κB signaling

Osteoporosis is an osteolytic disorder commonly associated with excessive osteoclast formation. Transcriptional coactivator with PDZ-binding motif (TAZ) is a key downstream effector of the Hippo signaling pathway; it was suggested to be involved in the regulation of bone homeostasis. However, the ex...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Wanlei, Lu, Xuanyuan, Zhang, Tan, Han, Weiqi, Li, Jianlei, He, Wei, Jia, Yewei, Zhao, Kangxian, Qin, An, Qian, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275679/
https://www.ncbi.nlm.nih.gov/pubmed/34253712
http://dx.doi.org/10.1038/s41413-021-00151-3