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Characterization of microglial transcriptomes in the brain and spinal cord of mice in early and late experimental autoimmune encephalomyelitis using a RiboTag strategy

Microglia play an important role in the pathogenesis of multiple sclerosis and the mouse model of MS, experimental autoimmune encephalomyelitis (EAE). To more fully understand the role of microglia in EAE we characterized microglial transcriptomes before the onset of motor symptoms (pre-onset) and d...

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Detalles Bibliográficos
Autores principales: Acharjee, Shaona, Gordon, Paul M. K., Lee, Benjamin H., Read, Justin, Workentine, Matthew L., Sharkey, Keith A., Pittman, Quentin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275680/
https://www.ncbi.nlm.nih.gov/pubmed/34253764
http://dx.doi.org/10.1038/s41598-021-93590-1