Mesenchymal stromal cells expressing a dominant‐negative high mobility group A1 transgene exhibit improved function during sepsis

High mobility group (HMG)A proteins are nonhistone chromatin proteins that bind to the minor groove of DNA, interact with transcriptional machinery, and facilitate DNA‐directed nuclear processes. HMGA1 has been shown to regulate genes involved with systemic inflammatory processes. We hypothesized th...

Descripción completa

Detalles Bibliográficos
Autores principales: Kwon, Min‐Young, Ghanta, Sailaja, Ng, Julie, Castano, Ana P., Han, Junwen, Ith, Bonna, Lederer, James A., El‐Chemaly, Souheil, Chung, Su Wol, Liu, Xiaoli, Perrella, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Host Defense and Pathophysiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275698/
https://www.ncbi.nlm.nih.gov/pubmed/33438259
http://dx.doi.org/10.1002/JLB.4A0720-424R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275698/
https://www.ncbi.nlm.nih.gov/pubmed/33438259
http://dx.doi.org/10.1002/JLB.4A0720-424R

Ejemplares similares