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Mesenchymal stromal cells expressing a dominant‐negative high mobility group A1 transgene exhibit improved function during sepsis
High mobility group (HMG)A proteins are nonhistone chromatin proteins that bind to the minor groove of DNA, interact with transcriptional machinery, and facilitate DNA‐directed nuclear processes. HMGA1 has been shown to regulate genes involved with systemic inflammatory processes. We hypothesized th...
Autores principales: | Kwon, Min‐Young, Ghanta, Sailaja, Ng, Julie, Castano, Ana P., Han, Junwen, Ith, Bonna, Lederer, James A., El‐Chemaly, Souheil, Chung, Su Wol, Liu, Xiaoli, Perrella, Mark A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275698/ https://www.ncbi.nlm.nih.gov/pubmed/33438259 http://dx.doi.org/10.1002/JLB.4A0720-424R |
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