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A HML6 endogenous retrovirus on chromosome 3 is upregulated in amyotrophic lateral sclerosis motor cortex

There is increasing evidence that endogenous retroviruses (ERVs) play a significant role in central nervous system diseases, including amyotrophic lateral sclerosis (ALS). Studies of ALS have consistently identified retroviral enzyme reverse transcriptase activity in patients. Evidence indicates tha...

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Detalles Bibliográficos
Autores principales: Jones, Ashley R., Iacoangeli, Alfredo, Adey, Brett N., Bowles, Harry, Shatunov, Aleksey, Troakes, Claire, Garson, Jeremy A., McCormick, Adele L., Al-Chalabi, Ammar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275748/
https://www.ncbi.nlm.nih.gov/pubmed/34253796
http://dx.doi.org/10.1038/s41598-021-93742-3