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Homeobox Gene Six3 is Required for the Differentiation of D2-Type Medium Spiny Neurons

Medium spiny neurons (MSNs) in the striatum, which can be divided into D1 and D2 MSNs, originate from the lateral ganglionic eminence (LGE). Previously, we reported that Six3 is a downstream target of Sp8/Sp9 in the transcriptional regulatory cascade of D2 MSN development and that conditionally knoc...

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Detalles Bibliográficos
Autores principales: Song, Xiaolei, Chen, Haotian, Shang, Zicong, Du, Heng, Li, Zhenmeiyu, Wen, Yan, Liu, Guoping, Qi, Dashi, You, Yan, Yang, Zhengang, Zhang, Zhuangzhi, Xu, Zhejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275777/
https://www.ncbi.nlm.nih.gov/pubmed/34014554
http://dx.doi.org/10.1007/s12264-021-00698-5