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Renal denervation does not affect hypertension or the renin-angiotensin system in a rodent model of juvenile-onset polycystic kidney disease: clinical implications

We examined the effect of total and afferent renal denervation (RDN) on hypertension and the renin-angiotensin system (RAS) in a rodent model of juvenile-onset polycystic kidney disease (PKD). Lewis Polycystic Kidney (LPK) and control rats received total, afferent or sham RDN by periaxonal applicati...

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Detalles Bibliográficos
Autores principales: Li, Sheran, Hildreth, Cara M., Rahman, Ahmed A., Barton, Sean A., Wyse, Benjamin F., Lim, Chai K., Pilowsky, Paul M., Phillips, Jacqueline K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275789/
https://www.ncbi.nlm.nih.gov/pubmed/34253766
http://dx.doi.org/10.1038/s41598-021-93575-0