Cefiderocol Activity Against Clinical Pseudomonas aeruginosa Isolates Exhibiting Ceftolozane-Tazobactam Resistance

BACKGROUND: Mutations in the AmpC-AmpR region are associated with treatment-emergent ceftolozane-tazobactam (TOL-TAZ) and ceftazidime-avibactam (CAZ-AVI) resistance. We sought to determine if these mutations impact susceptibility to the novel cephalosporin-siderophore compound cefiderocol. METHODS:...

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Detalles Bibliográficos
Autores principales: Simner, Patricia J, Beisken, Stephan, Bergman, Yehudit, Posch, Andreas E, Cosgrove, Sara E, Tamma, Pranita D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Major Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275882/
https://www.ncbi.nlm.nih.gov/pubmed/34262990
http://dx.doi.org/10.1093/ofid/ofab311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275882/
https://www.ncbi.nlm.nih.gov/pubmed/34262990
http://dx.doi.org/10.1093/ofid/ofab311

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