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BiasAway: command-line and web server to generate nucleotide composition-matched DNA background sequences

MOTIVATION: Accurate motif enrichment analyses depend on the choice of background DNA sequences used, which should ideally match the sequence composition of the foreground sequences. It is important to avoid false positive enrichment due to sequence biases in the genome, such as GC-bias. Therefore,...

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Detalles Bibliográficos
Autores principales: Khan, Aziz, Riudavets Puig, Rafael, Boddie, Paul, Mathelier, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275979/
https://www.ncbi.nlm.nih.gov/pubmed/33135764
http://dx.doi.org/10.1093/bioinformatics/btaa928