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Incorporating alignment uncertainty into Felsenstein’s phylogenetic bootstrap to improve its reliability

MOTIVATION: Most evolutionary analyses are based on pre-estimated multiple sequence alignment. Wong et al. established the existence of an uncertainty induced by multiple sequence alignment when reconstructing phylogenies. They were able to show that in many cases different aligners produce differen...

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Detalles Bibliográficos
Autores principales: Chang, Jia-Ming, Floden, Evan W, Herrero, Javier, Gascuel, Olivier, Di Tommaso, Paolo, Notredame, Cedric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275982/
https://www.ncbi.nlm.nih.gov/pubmed/30726875
http://dx.doi.org/10.1093/bioinformatics/btz082