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Computational Modeling of C-Terminal Tails to Predict the Calcium-Dependent Secretion of Endoplasmic Reticulum Resident Proteins

The lumen of the endoplasmic reticulum (ER) has resident proteins that are critical to perform the various tasks of the ER such as protein maturation and lipid metabolism. These ER resident proteins typically have a carboxy-terminal ER retention/retrieval sequence (ERS). The canonical ERS that promo...

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Detalles Bibliográficos
Autores principales: Trychta, Kathleen A., Xie, Bing, Verma, Ravi Kumar, Xu, Min, Shi, Lei, Harvey, Brandon K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276033/
https://www.ncbi.nlm.nih.gov/pubmed/34268295
http://dx.doi.org/10.3389/fchem.2021.689608