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PD-1(+)CXCR5(−)CD4(+) Th-CXCL13 cell subset drives B cells into tertiary lymphoid structures of nasopharyngeal carcinoma

BACKGROUND: A major current challenge is to exploit tertiary lymphoid structures (TLSs) to promote the lymphocyte infiltration, activation and differentiation by tumor antigens to increase antitumor immune responses. The mechanisms that underlie the role of TLS formation in the adaptive immune respo...

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Detalles Bibliográficos
Autores principales: Li, Jiang-Ping, Wu, Chang-You, Chen, Ming-Yuan, Liu, Shang-Xin, Yan, Shu-Mei, Kang, Yin-Feng, Sun, Cong, Grandis, Jennifer R, Zeng, Mu-Sheng, Zhong, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276302/
https://www.ncbi.nlm.nih.gov/pubmed/34253636
http://dx.doi.org/10.1136/jitc-2020-002101