Single-cell RNA sequencing reveals distinct cellular factors for response to immunotherapy targeting CD73 and PD-1 in colorectal cancer

BACKGROUND: Although cancer immunotherapy is one of the most effective advanced-stage cancer therapies, no clinically approved cancer immunotherapies currently exist for colorectal cancer (CRC). Recently, programmed cell death protein 1 (PD-1) blockade has exhibited clinical benefits according to on...

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Detalles Bibliográficos
Autores principales: Kim, Miok, Min, Yong Ki, Jang, Jinho, Park, Hyejin, Lee, Semin, Lee, Chang Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Immunotherapy Biomarkers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276303/
https://www.ncbi.nlm.nih.gov/pubmed/34253638
http://dx.doi.org/10.1136/jitc-2021-002503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276303/
https://www.ncbi.nlm.nih.gov/pubmed/34253638
http://dx.doi.org/10.1136/jitc-2021-002503

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