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zapERtrap: A light-regulated ER release system reveals unexpected neuronal trafficking pathways

Here we introduce zapalog-mediated endoplasmic reticulum trap (zapERtrap), which allows one to use light to precisely trigger forward trafficking of diverse integral membrane proteins from internal secretory organelles to the cell surface with single cell and subcellular spatial resolution. To demon...

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Detalles Bibliográficos
Autores principales: Bourke, Ashley M., Schwartz, Samantha L., Bowen, Aaron B., Kleinjan, Mason S., Winborn, Christina S., Kareemo, Dean J., Gutnick, Amos, Schwarz, Thomas L., Kennedy, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276314/
https://www.ncbi.nlm.nih.gov/pubmed/34241635
http://dx.doi.org/10.1083/jcb.202103186