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zapERtrap: A light-regulated ER release system reveals unexpected neuronal trafficking pathways
Here we introduce zapalog-mediated endoplasmic reticulum trap (zapERtrap), which allows one to use light to precisely trigger forward trafficking of diverse integral membrane proteins from internal secretory organelles to the cell surface with single cell and subcellular spatial resolution. To demon...
Autores principales: | Bourke, Ashley M., Schwartz, Samantha L., Bowen, Aaron B., Kleinjan, Mason S., Winborn, Christina S., Kareemo, Dean J., Gutnick, Amos, Schwarz, Thomas L., Kennedy, Matthew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276314/ https://www.ncbi.nlm.nih.gov/pubmed/34241635 http://dx.doi.org/10.1083/jcb.202103186 |
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