Small-molecule modulators of INAVA cytosolic condensate and cell–cell junction assemblies

Epithelial cells lining mucosal surfaces distinctively express the inflammatory bowel disease risk gene INAVA. We previously found that INAVA has dual and competing functions: one at lateral membranes where it affects mucosal barrier function and the other in the cytosol where INAVA enhances IL-1β s...

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Detalles Bibliográficos
Autores principales: Chang, Denis, Luong, Phi, Li, Qian, LeBarron, Jamie, Anderson, Michael, Barrett, Lee, Lencer, Wayne I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276315/
https://www.ncbi.nlm.nih.gov/pubmed/34251416
http://dx.doi.org/10.1083/jcb.202007177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276315/
https://www.ncbi.nlm.nih.gov/pubmed/34251416
http://dx.doi.org/10.1083/jcb.202007177

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