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Patient-Specific 3-Dimensional Model of Smooth Muscle Cell and Extracellular Matrix Dysfunction for the Study of Aortic Aneurysms

INTRODUCTION: Abdominal aortic aneurysms (AAAs) are associated with overall high mortality in case of rupture. Since the pathophysiology is unclear, no adequate pharmacological therapy exists. Smooth muscle cells (SMCs) dysfunction and extracellular matrix (ECM) degradation have been proposed as und...

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Detalles Bibliográficos
Autores principales: Bogunovic, Natalija, Meekel, Jorn P., Majolée, Jisca, Hekhuis, Marije, Pyszkowski, Jakob, Jockenhövel, Stefan, Kruse, Magnus, Riesebos, Elise, Micha, Dimitra, Blankensteijn, Jan D., Hordijk, Peter L., Ghazanfari, Samaneh, Yeung, Kak K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276336/
https://www.ncbi.nlm.nih.gov/pubmed/33902345
http://dx.doi.org/10.1177/15266028211009272