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Distinct nitrogen isotopic compositions of healthy and cancerous tissue in mice brain and head&neck micro-biopsies

BACKGROUND: Cancerous cells can recycle metabolic ammonium for their growth. As this ammonium has a low nitrogen isotope ratio ((15)N/(14)N), its recycling may cause cancer tissue to have lower (15)N/(14)N than surrounding healthy tissue. We investigated whether, within a given tissue type in indivi...

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Detalles Bibliográficos
Autores principales: Straub, M., Sigman, D. M., Auderset, A., Ollivier, J., Petit, B., Hinnenberg, B., Rubach, F., Oleynik, S., Vozenin, M.-C., Martínez-García, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276491/
https://www.ncbi.nlm.nih.gov/pubmed/34256713
http://dx.doi.org/10.1186/s12885-021-08489-x