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CHK Methylation Is Elevated in Colon Cancer Cells and Contributes to the Oncogenic Properties

Src is an important oncogene that plays key roles in multiple signal transduction pathways. Csk-homologous kinase (CHK) is a kinase whose molecular roles are largely uncharacterized. We previously reported expression of CHK in normal human colon cells, and decreased levels of CHK protein in colon ca...

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Detalles Bibliográficos
Autores principales: Zhu, Shudong, Zhu, Yan, Wang, Qiuwen, Zhang, Yi, Guo, Xialing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276677/
https://www.ncbi.nlm.nih.gov/pubmed/34268315
http://dx.doi.org/10.3389/fcell.2021.708038